Impressive Study Touts Mega Benefits From Resveratrol

This just in from our Dr Jamie McManus: 

The most significant human study to date, which supports the health-enhancing benefits of resveratrol that may address many of the chronic age-related diseases of our time, has just been published!

In a study published this month in Cell Metabolism, Dutch researchers showed that taking a resveratrol supplement for 30 days significantly lowered multiple markers associated with heart disease, diabetes, cancer, and many other chronic diseases. These include markers of inflammation, improved mitochondrial capacity, lowered blood pressure, and blood glucose.

Since inflammation is at the root of literally hundreds of diseases, this has immense potential health implications. And we know that chronic inflammation leads not only to age-related diseases but to accelerated aging, as well! This study also showed reductions in both blood pressure and triglyceride levels, both of which are associated with heart disease risk.

Diabetes has increased a whopping 35% in just the past decade. Until now, the only nonpharmacologic way to improve insulin sensitivity and reduce your risk of developing diabetes has been calorie restriction and weight loss—which is so very hard for people. This study would suggest that adding a high potency resveratrol supplement may help improve your insulin sensitivity and lower blood-sugar levels.

Anyone out there too tired to exercise? Well, this study may provide an answer for this, as well! These study participants showed significant increases in markers of mitochondrial function. Mitochondria are your body’s energy producers that tend to decrease in number and output as we age. The increases seen in this study were similar to those seen with endurance training. So get some of the energy benefits associated with exercise and ramp up your mitochondria just by taking a resveratrol supplement! Sounds too good to be true, but I must say the results here are compelling and exciting.

Dr Jamie’s advice is that, along with trying to eat better and exercise regularly, it makes better sense than ever to add in a high potency resveratrol supplement to your daily routine

Daily Glass of Polyphenols

The anti-aging french paradox and that have a daily glass of red wine thing…is their some validity to that ??

I have a product that is like drinking 100 glasses of wine a day without the hangover!

That’s a healthy dose of polyphenols!

If the polyphenols really do make such a difference I’d like me some of that.

Dr. Oz has spoken on Oprah about anti-aging, life regeneration, life prolonging, life extension pioneering and the significant value of resveratrol.

Resveratrol is a potent member of the class of natural, plant-derived chemicals known as polyphenols.  Diets high in fruits and vegetables containing polyphenols can reduce risk of a variety of health concerns.

The skin of the red grape is particularly rich in polyphenols and one of the significant ingredients in our anti-aging live longer tonic.

If you google resveratrol in relationship to cancer, diabetes or cardiovascular disease you will find oodles of research demonstrating it’s benefits.

Kindof cool.

Many resveratrol products are tainted with emodin — a laxative.  This is apparently done to give the effect of detoxification. As many as 50% of them are tainted.

Wow.  I totally didn’t know that.

Our resveratrol product is 98% pure.

The muscadine grape, which we use, is a super duper grape and has additional valuable and very unique chemical componants.

I am very proud to represent this astounding and truly beneficial anti-aging product.

A 30 day supply of our anti-aging tonic has the equivalent amount of resveratrol found in 3,000 glasses of red wine, and our exclusive ingredients are 10x more powerful in slowing a key mechanism of aging than resveratrol alone*.


cellular red wine bubble flickr image credit

Resveratrol For Your Heart And Immunity

Ending my posts about heart health and beginning this month’s conversation about seasonal allergies and immunity. I thought of the profound impact of polyphenols.  Not all are created equal! These notes are designed by the company.  Informative!

Below is a slightly edited version of notes from an informative field call that I thought you might find of interest.

What intrigues me about this product is the research, the sourcing of the most supreme grape known to man and finding a way to safely assimilate it in a concentrate for supplementation.

Past that, the testimonies and health impact this product has had during the release have been pretty darn astounding!

Here is the conversation from the call – enjoy!

Hello, I’m Cindy Latham, Senior Vice President of Marketing. And I’m here today with Dr. Jamie McManus, a physician and Chairman of Medical Affairs, Health Sciences and Education and Dr. Carsten Smidt, Chief Scientific Officer, to tell you about our revolutionary resveratrol product.

But, before I do so, Let me just ask the question…How would you like to feel 25 years younger and live 25 years longer? Really, isn’t that everyone’s dream? Exploring longevity is truly the ultimate scientific quest and researchers are spending billions of dollars to unlock the science of living longer.

I’m proud to report that our company, the number one natural nutrition company, is on the forefront of this scientific research. Our scientists have designed a way to create a unique polyphenol blend shown in laboratory studies to fight cellular aging. As a result, we have developed the world’s best anti-aging supplement. This breakthrough Cellular Anti-Aging Tonic, has filed patent applications to protect this unique and exclusive blend of polyphenols.*

Just one of the ingredients in our anti-aging tonic - resveratrol, has been referenced in over 2000 research publications, including studies conducted by Harvard University, the National Institute on Aging, National Cancer Institute and the National Institute of Environmental Health Sciences.

But here’s the most exciting news, a 30-day supply delivers the equivalent amount of resveratrol found in 3,000 glasses of red wine. That means just one teaspoon delivers the equivalent amount of resveratrol found in 100 glasses of red wine. The ingredients, with their unique polyphenol profile, have been shown in laboratory studies to be ten times more powerful in slowing a key mechanism of aging than resveratrol alone.*

It took scientists years of research to create this incredible, all natural, patent-pending breakthrough in cellular anti-aging product which is absolutely exclusive to our company.*

How does it work? Well, in laboratory studies,our formula has been shown to impact the four key mechanisms of cellular aging.*

That’s what you’re going to learn about next.

Please welcome our own, Dr. Jamie McManus, to share more of this product story with you.

Dr. Jamie McManus

Hello, I’m so excited to share the science our revolutionary cellular anti-aging breakthrough supplement.* But before we talk about the specific features of this remarkable dietary supplement, let’s get a few facts straight about aging. First of all, contrary to popular belief, aging is not something that happens when we’re…well, old.

Research actually shows that as soon as we finish growing, in our late teens, we start to age. You may not see aging at this young age, but that is because it all begins at the cellular level.

So is aging inevitable? Well, to answer that question, it’s important to differentiate between biologic aging and chronologic aging. We obviously can’t slow down time. With each passing year we do become a year older. But it appears that we may be able to impact biologic aging. This has to do with how efficiently our cells repair and replicate themselves. There are actually four key mechanisms of aging that occur on the cellular level. But let’s start with a little cell physiology lesson first.

At the center of every cell is a nucleus where the DNA resides. DNA carries genetic information for our physical characteristics and defines each cell’s function. Outside the nucleus in the cellular fluid are mitochondria, the organelles in the body’s cells, that generate energy to power the cell’s activities.

If everything works perfectly, the DNA in each cell is well protected and repaired, so it can be copied correctly when the cell divides. And mitochondria effectively generate energy, so all the systems of your body operate at maximum efficiency.

Unfortunately, everything doesn’t work perfectly, and every day, every cell in your body is bombarded by up to a million DNA damaging assaults─from things like an unhealthy diet, toxins in the environment, smoking…you name it, assaults come from everywhere. They’re even a by-product of your own metabolism. These assaults can damage the cell’s database, creating something like a typo that may compromise cellular function and ultimately longevity. If they’re not repaired, some typos can be replicated over and over again as cells divide. Unfortunately, over time our cells become less efficient at preventing and repairing this DNA damage. This DNA damage is the first mechanism of cellular aging that we refer to.

The second mechanism of cellular aging is a class of compounds called genetic regulators which can contribute to age-related cellular deterioration. These genetic regulators in our cells control the dynamic balance between damage and repair, including whether a cell lives or dies. As the years go by, the activity of these genetic regulators promoting cell renewal and energy production declines, while genetic regulators promoting cell death become more active. As natural defenses and self-repair functions decline, cumulative cell damage increases and this cumulative damage throughout life contributes to age-related cellular deterioration.

The third cause of cellular aging is declining cellular energy production. It’s in the cell’s m
itochondria that energy is created to run all the cellular functions. But over time, mitochondrial efficiency naturally decreases, leading to a decline in energy production which then affects cell function.

And the fourth way cells age is by accumulation of something called Advanced Glycation End Products, or what are commonly called AGE proteins. They’re a bit like plaque that builds up on your teeth, or in your arteries over time. As your cell functions, bringing nutrients in and eliminating waste, this plaque is a byproduct which begins to stick and build up inside the cells, compromising cellular integrity, cell function and ultimately, longevity.

Now for the good news! Laboratory studies show that the key ingredients in our productimpact all four of these mechanisms of cellular aging.*

First, our polyphenols have been shown to effectively help protect and repair cellular DNA.*

Second, our polyphenols have been shown to positively impact genetic regulators which help fight cellular aging.

Third, our polyphenols have been shown to promote mitochondrial biogenesis, which helps increase power production within the cells.*

And finally, our polyphenols also reduced the formation of those AGE proteins that can gradually clog up your cells. In fact laboratory studies demonstrate that the ingredients in our product are 10 times more powerful than resveratrol alone in slowing AGE protein formation.*

OurAnti-Aging Tonic, truly is the revolutionary breakthrough we’ve been waiting for because it harnesses the power of a unique polyphenol blend to impact the four key mechanisms of cellular aging.*

The ingredients support heart health, brain health and cardiovascular function. They also enhance immunity and support joint health.*

The ingredients also promote cellular longevity, increase cellular energy, fight free radicals, and promote good health and well being.

And, of course, because it’s from our companyit is all natural with no artificial colors, flavors, sweeteners or preservatives.

My colleague Dr. Carsten Smidt, Chief Scientific Officer, is here to share more about the exclusive ingredients in our anti-aging formulation.

Carsten?

Dr. Carsten R. Smidt

One of the most exciting areas in longevity research has been the study of the genetic regulators of aging. Recently, scientists identified in laboratory studies that resveratrol—a compound found in red wine—activates genetic longevity regulators inside cells called sirtuins, which have positive effects on DNA health and metabolism.

Today, as Cindy said, there are over 2000 research publications about resveratrol.

Now, the science team took this very exciting research to the next level to create our product─ first by sourcing the purest and most potent resveratrol. That’s no easy task since the vast majority of resveratrol sources on today’s market are not pure enough. They often contain substantial amounts of unwanted compounds that can cause tolerance problems. To avoid these issues, we identified a novel, natural resveratrol source that is the purest available.

Then our scientists zeroed in on a remarkable super grape, known as Vitis rotundifolia. This is the only grape in nature with an extra chromosome – which scientists believe greatly enhances its polyphenol profile and potential health benefits.

After much research, we identified and selected the most potent varieties of this super grape. Then, together with scientists from the University of Georgia, we created a carefully designed extraction process to guarantee the highest possible biological activity. We tried many different processes, and we chose the one that gave us the highest biological efficacy in a series of anti-aging laboratory tests. This gentle, efficient extraction process resulted in a super-grape extract high in ellagic acid, which is a phytonutrient not found in ordinary grapes. Ellagic acid is responsible for many of the unique cellular anti-aging actions of the super grape in our formulation. In addition, the extract supplies many other potent polyphenols affecting cellular longevity pathways, such as phenolic acids, ellagitannins, anthocyanins, and proanthocyanidins.*

By harnessing the special cellular anti-aging power of this super grape and combining it with ultrapure, natural resveratrol our scientists have achieved a real breakthrough in the fight against cellular aging.*

In fact, this is the most complex product ever developed by our science team. That’s because of the challenges to develop a new extract from scratch and to combine it into the highly concentrated and potent liquid formula.Moreover, knowing the enormous health benefits of this super grape, we were able to secure the entire output from the largest and best growers in the world, and have filed patents to protect this exclusive and innovative polyphenol formulation.*

A 30-day supply delivers the equivalent amount of resveratrol found in 3,000 glasses of wine. That means just one teaspoon a day delivers the equivalent amount of resveratrol provided in 100 glasses of red wine. And with the inclusion of our exclusive super grape extract, the ingredients have been shown in laboratory studies to be 10 times more powerful than resveratrol alone at slowing the formation of AGE proteins.*

You won’t find another product like this on the market. It took years of research and ingenuity─ first to identify the unique polyphenol profile of this super grape, then to secure the entire output from the largest and best growers in the world, and finally to develop a unique, proprietary extraction process. The result is a remarkable tonic with ingredients that have been research tested to address the four key mechanisms of aging.* It is so exclusive, we have applied for patents to protect our intellectual property so no one can duplicate it.

Cindy Latham

So don’t wait another minute. Turn to the #1 natural nutrition company in the United States, and take positive action today. Try our Cellular Anti-Aging Tonic, the world’s best cellular anti-aging dietary supplement, and find out, first hand, what the excitement is all about.*

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Everything You Ever Wanted To Know About Resveratrol

Below is a slightly edited version of an informative field call that I thought you might find of interest.

What intrigues me about this product is the research, the sourcing of the most supreme grape known to man and finding a way to safely assimilate it in a concentrate for supplementation.

Past that, the testimonies and health impact this product has had during this last year and a half have been astounding!

Here is the conversation from the call – enjoy!

Hello, I’m Cindy Latham, Senior Vice President of Marketing. And I’m here today with Dr. Jamie McManus, a physician and Chairman of Medical Affairs, Health Sciences and Education and Dr. Carsten Smidt, Chief Scientific Officer, to tell you about our revolutionary resveratrol product.

But, before I do so, Let me just ask the question…How would you like to feel 25 years younger and live 25 years longer? Really, isn’t that everyone’s dream? Exploring longevity is truly the ultimate scientific quest and researchers are spending billions of dollars to unlock the science of living longer.

I’m proud to report that our company, the number one natural nutrition company, is on the forefront of this scientific research. Our scientists have designed a way to create a unique polyphenol blend shown in laboratory studies to fight cellular aging. As a result, we have developed the world’s best anti-aging supplement. This breakthrough Cellular Anti-Aging Tonic, has filed patent applications to protect this unique and exclusive blend of polyphenols.*

Just one of the ingredients in our anti-aging tonic - resveratrol, has been referenced in over 2000 research publications, including studies conducted by Harvard University, the National Institute on Aging, National Cancer Institute and the National Institute of Environmental Health Sciences.

But here’s the most exciting news, a 30-day supply delivers the equivalent amount of resveratrol found in 3,000 glasses of red wine. That means just one teaspoon delivers the equivalent amount of resveratrol found in 100 glasses of red wine. The ingredients, with their unique polyphenol profile, have been shown in laboratory studies to be ten times more powerful in slowing a key mechanism of aging than resveratrol alone.*

It took scientists years of research to create this incredible, all natural, patent-pending breakthrough in cellular anti-aging product which is absolutely exclusive to our company.*

How does it work? Well, in laboratory studies, our formula has been shown to impact the four key mechanisms of cellular aging.*

That’s what you’re going to learn about next.

Please welcome our own, Dr. Jamie McManus, to share more of this product story with you.

Dr. Jamie McManus

Hello, I’m so excited to share the science our revolutionary cellular anti-aging breakthrough supplement.* But before we talk about the specific features of this remarkable dietary supplement, let’s get a few facts straight about aging. First of all, contrary to popular belief, aging is not something that happens when we’re…well, old.

Research actually shows that as soon as we finish growing, in our late teens, we start to age. You may not see aging at this young age, but that is because it all begins at the cellular level.

So is aging inevitable? Well, to answer that question, it’s important to differentiate between biologic aging and chronologic aging. We obviously can’t slow down time. With each passing year we do become a year older. But it appears that we may be able to impact biologic aging. This has to do with how efficiently our cells repair and replicate themselves. There are actually four key mechanisms of aging that occur on the cellular level. But let’s start with a little cell physiology lesson first.

At the center of every cell is a nucleus where the DNA resides. DNA carries genetic information for our physical characteristics and defines each cell’s function. Outside the nucleus in the cellular fluid are mitochondria, the organelles in the body’s cells, that generate energy to power the cell’s activities.

If everything works perfectly, the DNA in each cell is well protected and repaired, so it can be copied correctly when the cell divides. And mitochondria effectively generate energy, so all the systems of your body operate at maximum efficiency.

Unfortunately, everything doesn’t work perfectly, and every day, every cell in your body is bombarded by up to a million DNA damaging assaults─from things like an unhealthy diet, toxins in the environment, smoking…you name it, assaults come from everywhere. They’re even a by-product of your own metabolism. These assaults can damage the cell’s database, creating something like a typo that may compromise cellular function and ultimately longevity. If they’re not repaired, some typos can be replicated over and over again as cells divide. Unfortunately, over time our cells become less efficient at preventing and repairing this DNA damage. This DNA damage is the first mechanism of cellular aging that we refer to.

The second mechanism of cellular aging is a class of compounds called genetic regulators which can contribute to age-related cellular deterioration. These genetic regulators in our cells control the dynamic balance between damage and repair, including whether a cell lives or dies. As the years go by, the activity of these genetic regulators promoting cell renewal and energy production declines, while genetic regulators promoting cell death become more active. As natural defenses and self-repair functions decline, cumulative cell damage increases and this cumulative damage throughout life contributes to age-related cellular deterioration.

The third cause of cellular aging is declining cellular energy production. It’s in the cell’s m
itochondria that energy is created to run all the cellular functions. But over time, mitochondrial efficiency naturally decreases, leading to a decline in energy production which then affects cell function.

And the fourth way cells age is by accumulation of something called Advanced Glycation End Products, or what are commonly called AGE proteins. They’re a bit like plaque that builds up on your teeth, or in your arteries over time. As your cell functions, bringing nutrients in and eliminating waste, this plaque is a byproduct which begins to stick and build up inside the cells, compromising cellular integrity, cell function and ultimately, longevity.

Now for the good news! Laboratory studies show that the key ingredients in our product impact all four of these mechanisms of cellular aging.*

First, our polyphenols have been shown to effectively help protect and repair cellular DNA.*

Second, our polyphenols have been shown to positively impact genetic regulators which help fight cellular aging.

Third, our polyphenols have been shown to promote mitochondrial biogenesis, which helps increase power production within the cells.*

And finally, our polyphenols also reduced the formation of those AGE proteins that can gradually clog up your cells. In fact laboratory studies demonstrate that the ingredients in our product are 10 times more powerful than resveratrol alone in slowing AGE protein formation.*

OurAnti-Aging Tonic, truly is the revolutionary breakthrough we’ve been waiting for because it harnesses the power of a unique polyphenol blend to impact the four key mechanisms of cellular aging.*

The ingredients support heart health, brain health and cardiovascular function. They also enhance immunity and support joint health.*

The ingredients also promote cellular longevity, increase cellular energy, fight free radicals, and promote good health and well being.

And, of course, because it’s from our company it is all natural with no artificial colors, flavors, sweeteners or preservatives.

My colleague Dr. Carsten Smidt, Chief Scientific Officer, is here to share more about the exclusive ingredients in our anti-aging formulation.

Carsten?

Dr. Carsten R. Smidt

One of the most exciting areas in longevity research has been the study of the genetic regulators of aging. Recently, scientists identified in laboratory studies that resveratrol—a compound found in red wine—activates genetic longevity regulators inside cells called sirtuins, which have positive effects on DNA health and metabolism.

Today, as Cindy said, there are over 2000 research publications about resveratrol.

Now, the science team took this very exciting research to the next level to create our product ─ first by sourcing the purest and most potent resveratrol. That’s no easy task since the vast majority of resveratrol sources on today’s market are not pure enough. They often contain substantial amounts of unwanted compounds that can cause tolerance problems. To avoid these issues, we identified a novel, natural resveratrol source that is the purest available.

Then our scientists zeroed in on a remarkable super grape, known as Vitis rotundifolia. This is the only grape in nature with an extra chromosome – which scientists believe greatly enhances its polyphenol profile and potential health benefits.

After much research, we identified and selected the most potent varieties of this super grape. Then, together with scientists from the University of Georgia, we created a carefully designed extraction process to guarantee the highest possible biological activity. We tried many different processes, and we chose the one that gave us the highest biological efficacy in a series of anti-aging laboratory tests. This gentle, efficient extraction process resulted in a super-grape extract high in ellagic acid, which is a phytonutrient not found in ordinary grapes. Ellagic acid is responsible for many of the unique cellular anti-aging actions of the super grape in our formulation. In addition, the extract supplies many other potent polyphenols affecting cellular longevity pathways, such as phenolic acids, ellagitannins, anthocyanins, and proanthocyanidins.*

By harnessing the special cellular anti-aging power of this super grape and combining it with ultrapure, natural resveratrol our scientists have achieved a real breakthrough in the fight against cellular aging.*

In fact, this is the most complex product ever developed by our science team. That’s because of the challenges to develop a new extract from scratch and to combine it into the highly concentrated and potent liquid formula. Moreover, knowing the enormous health benefits of this super grape, we were able to secure the entire output from the largest and best growers in the world, and have filed patents to protect this exclusive and innovative polyphenol formulation.*

A 30-day supply delivers the equivalent amount of resveratrol found in 3,000 glasses of wine. That means just one teaspoon a day delivers the equivalent amount of resveratrol provided in 100 glasses of red wine. And with the inclusion of our exclusive super grape extract, the ingredients have been shown in laboratory studies to be 10 times more powerful than resveratrol alone at slowing the formation of AGE proteins.*

You won’t find another product like this on the market. It took years of research and ingenuity─ first to identify the unique polyphenol profile of this super grape, then to secure the entire output from the largest and best growers in the world, and finally to develop a unique, proprietary extraction process. The result is a remarkable tonic with ingredients that have been research tested to address the four key mechanisms of aging.* It is so exclusive, we have applied for patents to protect our intellectual property so no one can duplicate it.

Cindy Latham

So don’t wait another minute. Turn to the #1 natural nutrition company in the United States, and take positive action today. Try our Cellular Anti-Aging Tonic, the world’s best cellular anti-aging dietary supplement, and find out, first hand, what the excitement is all about.*

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Have A Glass Of Resveratrol

Dr. Oz spoke on Oprah about anti-aging, life regeneration, life prolonging, life extension pioneering and the significant value of resveratrol.

Resveratrol is a potent member of the class of natural, plant-derived chemicals known as polyphenols.  Diets high in fruits and vegetables containing polyphenols can reduce risk of a variety of health concerns.

The skin of the red grape is particularly rich in polyphenols and one of the significant ingredients in our anti-aging live longer tonic.

If you google resveratrol in relationship to cancer, diabetes or cardiovascular disease you will find oodles of research demonstrating it’s benefits.

Kindof cool.

Many resveratrol products are tainted with emodin — a laxative.  This is apparently done to give the effect of detoxification. As many as 50% of them are tainted.

Wow.  I totally didn’t know that.

Our resveratrol product is 98% pure.

The muscadine grape, which we use, is a super duper grape and has additional valuable and very unique chemical componants.

I am very proud to represent this astounding and truly beneficial anti-aging product.

A 30 day supply of our anti-aging tonichas the equivalent amount of resveratrol found in 3,000 glasses of red wine, and our exclusiveingredients are 10x more powerful in slowing a key mechanism of aging than resveratrol alone*.

I like to say it’s like drinking 100 glasses of wine a day without the hangover!


cellular red wine bubble flickr image credit